Among the following, which benzodiazepine is often used for its effective anxiolytic properties?

Chlordiazepoxide is recognized for its effective anxiolytic properties, making it a common choice in the treatment of anxiety disorders. As one of the earliest benzodiazepines developed, it works by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, resulting in a calming effect on the central nervous system. This mechanism is central to its use in alleviating symptoms of anxiety.

In contrast, other substances listed, such as eszopiclone and zolpidem, are primarily used for the treatment of insomnia and are not classified as anxiolytics. They are designed to facilitate sleep rather than explicitly target anxiety symptoms. Buspirone, while also an anxiolytic, functions differently, primarily as a serotonin receptor agonist and not as a benzodiazepine. This differentiates it in terms of efficacy and onset of action compared to traditional benzodiazepines like chlordiazepoxide.

In summary, chlordiazepoxide is specifically utilized for its direct anxiolytic effects within the benzodiazepine class, making it the appropriate choice when addressing anxiety treatment.