What is the range of moderate lithium toxicity levels?

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Moderate lithium toxicity is typically defined within the range of 1.5 to 2.0 mEq/L. The choice indicating a range of 2.0 to 2.5 mEq/L is generally considered indicative of more severe toxicity.

In understanding lithium levels, it's critical to recognize that lithium is a mood stabilizer used primarily in the treatment of bipolar disorder and is associated with a narrow therapeutic window. Levels above 1.5 mEq/L may start to produce side effects such as gastrointestinal disturbances, tremors, and increased reflexes, moving into moderate toxicity.

As lithium levels rise and reach 2.0 – 2.5 mEq/L, symptoms can escalate to more significant neurological effects, such as confusion, ataxia, and even seizures, which falls into the category of severe toxicity rather than moderate.

This distinction is essential for clinicians to ensure proper monitoring and management of patients taking lithium, emphasizing the importance of regular serum level checks to avoid complications.

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