Which of the following is a sign of opiate intoxication?

Opiate intoxication is characterized by a range of symptoms that reflect the depressant effects of opioids on the central nervous system. One of the classic signs of opiate intoxication is slurred speech. This occurs because opioids depress the neural pathways involved in coordination and fine motor control, which includes articulate speech. As a result, individuals under the influence of opioids may display impaired speech that is slow or difficult to understand.

Pupil constriction, not dilation, is a hallmark of opiate intoxication, as opioids typically cause miosis (pinpoint pupils). Additionally, opiate intoxication can lead to decreased respiratory rates rather than increased, as opioids are known for depressing respiratory drive. Restlessness is more often associated with withdrawal from opioids rather than intoxication, as individuals may feel agitated and uncomfortable when the effects of the drug are wearing off. Thus, slurred speech serves as a key indicator of opiate intoxication, highlighting the drug's impact on motor control and cognitive function.