Which of the following is a mid-late sign of Alzheimer's dementia?

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Agraphia, which refers to the loss of the ability to communicate through writing, is indeed recognized as a mid-late sign of Alzheimer's dementia. This symptom typically emerges as the disease progresses and affects the patient's cognitive functions more severely. As Alzheimer's advances, individuals may experience significant impairments in their language capabilities and expressive skills, which includes writing.

In earlier stages of Alzheimer's, memory loss is often more pronounced and is considered an early indicator of the condition. Denial of illness might also be observed at various stages but is not specific to mid-late Alzheimer’s, as it can occur earlier in the disease process when patients are still somewhat aware of their condition. Poor decision-making can happen throughout the course of dementia, but it is usually more noticeable in the earlier to mid-stages and can manifest in various ways that may not distinctly categorize it as a hallmark of the later stages.

Agraphia represents a direct cognitive decline that is more likely to be associated with advanced stages of dementia when individuals can struggle with writing and other communicative tasks. Thus, identifying it as a mid-late sign is appropriate, reflecting the progression of cognitive decline typical in Alzheimer’s disease.

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