Which of the following is not a common side effect of Monoamine Oxidase Inhibitors (MAOIs)?

Fatigue is not typically recognized as a common side effect of Monoamine Oxidase Inhibitors (MAOIs). MAOIs primarily affect neurotransmitter levels by inhibiting the enzyme monoamine oxidase, which can lead to a range of side effects, but fatigue is less frequently reported than others.

Common side effects associated with MAOIs include dizziness, which can result from orthostatic hypotension linked to these medications. Weight gain can also occur, although it may depend on individual factors and the specific agent used. Difficulty initiating urination can arise in some patients, particularly among those with underlying urinary tract issues or other medications that might impact bladder function.

Understanding these medications and their side effects is critical for safe prescribing and monitoring, especially since MAOIs require dietary restrictions to avoid hypertensive crises from tyramine interactions.